Isaac Noott was appointed surgeon in the Royal Navy in 1808.
Marriage on 30 July 1816 at Plymouth of Isaac Noot Esq. of Haverfordwest, to Henrietta, daughter of William Gregg Esq. of Plymouth.
EARLY NAVAL CAREER
Appointed to the Tribune in 1818 - 
Appointed to the Revolutionaire in 1819 
Appointed to the Bellette in 1822 
Appointed to the Nimrod in 1824 
Appointed to the Alfred in 1831.
Appointed to the Stag in September 1834
He was employed as surgeon superintendent on two convict ships to Australia:
Bengal Merchant departed Sheerness 28 March 1838 and arrived in Port Jackson 21st July 1838. Isaac Noott departed Sydney for London on the Kinnear on 21st August 1838 
Layton departed Portsmouth 13 July 1839 and arrived in VDL 7 December 1839.
H.M.S. MEDEA 1840
Isaac Noott was on a list of Officers and Marines who served on board Her Majesty's Steam vessel Medea commanded by Frederick Barden Esq., employed on the coasts of Syria and Egypt in favour of the cause of his Imperial Majesty the Sultan.
An explosion took place on the Medea on the morning of 20th November 1840. One man was killed and several others including Isaac Noot who was in the gun room at the time were seriously injured .
ROYAL SOVEREIGN YACHT 1841
In 1841 he was on the list of Surgeons of the Royal Navy who were fit for service; he was appointed to the Royal Sovereign yacht in that same year.
Isaac Noott died in 1843.
Surgeon Isaac Noott, R.N. (1808), Pembroke dockyard, was distinguished for his war services; served in the boats of the Meleagar, at the capture of a privateer off Cuba (1808); was surgeon of the Tweed at the taking of Martinique, 1809; and of the Blake, on the coast of Catatonia in 1812, and the following year. Mr. Noott was one of the sufferers from the explosion of a shell on board the Medea steam vessel, off Alexandria, in 1840, having been severely wounded on that occasion. 
NOTES AND LINKS
1). Death - Noott - On the 15th inst. at The Uplands, Brading, Isle of Wight, Edward Gregg Noott, Esq., late Surgeon 2nd (Queen's Royal) Regiment, and youngest son of the late Isaac Noott Esq., Surgeon Royal Navy, aged 35. 
2). National Archives. Reference: PROB 11/1995/221 Description: Will of Isaac Noott, Surgeon Royal Navy of Whitehall near Pembroke , Pembrokeshire Date: 07 March 1844
3). National Archives. Reference: ADM 101/42/8A/1 Description: Folio 1: Sick book. Convict ship Layton between the 12th of June 1839 and 14th of December 1839. Isaac Noott, Surgeon